Alphavirus Encephalomyelitis: Mechanisms and Approaches to Prevention of Neuronal Damage

The effect of silymarin on prevention of hippocampus neuronal damage in rats with temporal lob epilepsy

Background and Objective: Temporal lobe epilepsy is hallmarked with neuronal degeneration in some areas of hippocampus and mossy fiber sprouting in dentate area. Considering some evidences on neuroprotective and antioxidant activity of silymarin (SM), this study was undertaken to evaluate the preventive effect of this agent on structural changes in hippocampus of kainate-epileptic rats. Materia...

[Bullying: current research approaches to diagnosis, mechanisms and prevention].

EQUINE ENCEPHALOMYELITIS (Eastern and Western) SUMMARY Eastern and Western equine encephalomyelitis viruses belong to the genus Alphavirus of the family

Eastern and Western equine encephalomyelitis viruses belong to the genus Alphavirus of the family Togaviridae. Alternate infection of birds and mosquitoes maintain these viruses in nature. The disease occurs sporadically in horses and humans from mid-summer to late autumn. Horses and humans are tangential dead-end hosts. The disease in horses is characterised by fever, anorexia, and severe depr...

Recruitment and retention of B cells in the central nervous system in response to alphavirus encephalomyelitis.

Sindbis virus (SINV) infection of neurons results in nonfatal viral encephalomyelitis and provides a model system for understanding recovery from virus infection of the central nervous system (CNS). Infection is followed by clearance of infectious virus, a gradual decrease in viral RNA, and then long-term maintenance of low levels of viral RNA. Antibody to the E2 glycoprotein is important for v...

Eastern and Western equine encephalomyelitis viruses belong to the genus Alphavirus of the family

Togaviridae. Alternate infection of birds and mosquitoes maintain these viruses in nature. The disease occurs sporadically in horses and humans from mid-summer to late autumn. Horses and humans are tangential dead-end hosts. The disease in horses is characterised by fever, anorexia, and severe depression. In severe cases, the disease in horses progresses to hyperexcitability, blindness, ataxia,...